General medicine elogs

This is an online E log book to discuss our patient's de-identified health data shared after taking his/her/guardian's signed informed consent. Here we discuss our individual patient's problems through series of inputs from available global online community of experts with an aim to solve those patient's clinical problems with collective current best evidence based inputs. This E log book also reflects my patient-centered online learning portfolio and your valuable inputs on the comment 29 year old male who is a daily wage labourer resident of Nalgonda, came to hospital with   chief complaints on & off fever since 2 yrs , shortness of breath , b/l pedal edema , abdominal distension and decreased urine output since 1 year History of present illness : Patient was apparently asymptomatic 2years ago and then one day he developed  fever  (high grade , continuous , associated with chills & rigors) and  generalized body aches  for which he went to a local RMP a...

I have given this case to solve and understand about " Patient clinical analysis " With given history and provided clinical investigations.  Clinical problems in patient: Migraine Kidney dysfunction - oligouria Swelling Sleep disturbances Left hand numbness Poor vision Broken leg Autism Intolerance to some kind of food Reasons for problems: From given data it could be from G 6 PD deficiency and AMPD 1 deficiency Sleep deprivation is due reduce synthesis of amino acids like adenosine defiency which is inhibitory to brain.  Kidney dysfunction is due to decrease in atp synthesis which also explains increase in intake of salt Swelling is due to g6pd defiency Others symtoms are due to genetic abnormalties like: Seattle type G6PD deficiency AMPD1 - AMPD1 deficiency heterozygous MTHFR - homozygous for C677T of MTHFR = 10-20% efficiency in processing folic acid = high homocysteine, low B12 and folate levels WNK1 mutation HLA-DRA - 3x higher risk for developing a peanut allergy In pop...